Toll-like receptors that sense viral infection

role of toll-like receptors in tuberculosis infection

background one-third of the world’s population is infected with mycobacterium tuberculosis. investigation of toll-like receptors (tlrs) has revealed new information regarding the immunopathogenesis of this disease. toll-like receptors can recognize various ligands with a lipoprotein structure in the bacilli. toll-like receptor 2 and tlr-4 have been identified in association with tuberculosis in...

Increased Expression of Toll-Like Receptors 2 and 4 in Renal Transplant Recipients that Develop Allograft Dysfunction: A Cohort Study

Background: The incidence of ischemic reperfusion injury (IRI) in early phase post-transplantation and activation of toll-like receptor (TLR-2) and TLR-4 remarkably impact the outcome of a renal allograft. Objective: To investigate whether the expression of TLRs in peripheral blood mononuclear cells (PBMCs) can predict the clinical outcome of kidney allografts. Methods: We obtained blood sample...

I-23: Reproduction and Toll Like Receptors(TLRs

Female and male reproductive tracts are of interest sites to study of immune system because they encounter specific infections such as those are sexually transmitted. Furthermore, female reproductive tract is in close contact with allogenic sperms and transmitted microorganisms during intercourse and semi allogenic fetus during pregnancy. In mammals, there are two types of immune responses, the...

Toll Like Receptors in Chronic Viral Hepatitis – Friend and Foe

contemplating the importance of toll-like receptors i and ii regarding human viral pathogenesis

conclusions to date, a large number of viruses are proved to trigger innate immunity via tlrs, suggesting that these receptors are likely to be important in the outcome of viral infection. this suggestion is supported by the observation that many viruses have evolved mechanisms not only to evade the innate immune system, but also to subvert it for the benefit of the virus. materials and methods...